Nedley

SAMe 400mg

$61.95

Omne Diem SAMe. S-Adenosylmethionine (SAMe) is a naturally occurring compound found in almost every tissue and fluid in the body. It is involved in many important processes associated with mood, joints, and liver.*

Mood Support

SAMe supplementation helps support sustained emotional well-being by promoting the production and break down of brain chemicals, such as serotonin, melatonin, and dopamine.*

Liver Health

SAMe helps restore and maintain healthy liver functions and detoxification by converting into glutathione; helping the liver combat oxidative stress, cellular damage, free radical activity and DNA breakdown.*

Joint Comfort

SAMe supplementation helps support cartilage and joint comfort and function by promoting native proteoglycan synthesis and secretion as well as other mechanisms.*




Joint Comfort: SAMe supports joint health and comfort, promoting mobility and flexibility for an active lifestyle.

Mood Support: Experience improved mood and emotional well-being with SAMe, promoting a positive outlook and greater resilience.

Liver Health: Support optimal liver function with SAMe, aiding in detoxification and promoting overall liver health.

Serving Size: 1 Tablet

Servings Per Container: 30

Amount Per Serving

S-Adenosylmethionine (SAMe) (from 400 mg of Ademetionine 1, 4-Butanedisulfonate)

Other Ingredients: Microcystalline Cellulose, Crospovidone, Colloidal Silicon Dioxide, Magnesium Stearate.

1-2 Tablets per day or as recommended by your healthcare provider

Meet our founder

Neil Nedley, MD, the founder and medical director of the Nedley Depression and Anxiety Recovery Programs™, is a leading voice in the world of mental well-being.

With years of experience as a practicing physician, prolific author, public speaker, and teacher, Dr. Nedley has devoted his career to transforming lives through lifestyle and holistic medicine.

His keen insights into depression, anxiety, mood, and cognitive function led him to eventually create his own supplement line with Nedley Health.