6 Ways Nedley Health’s Mood Supplement Supports Emotional Well-Being — Naturally
Once seen as less effective than prescriptions, natural mood support is now backed by hundreds of studies — with results equal to or better than antidepressants for mild symptoms, but without the same side effect concerns. Mood uses a proven, doctor-developed formula to help you feel steady, calm, and like yourself again.
1
Two Proven Mood-Boosting Nutrients — One Potent Formula
Mood is the first supplement to combine SAMe and saffron — a clinically studied duo that works on multiple pathways for emotional balance. Together, they can help lift mood, promote calm, and improve daily resilience more effectively than either ingredient alone.
💬 Think: more days of feeling steady, optimistic, and like yourself again.
2
Clinically Shown to Ease Stress and Low Mood
Multiple double-blind studies have found saffron to be as effective as certain antidepressants for mild-to-moderate symptoms — with no reported side effects. In one trial, participants saw improved mood and better social connection after just 8 weeks.
🌿 Fun fact: It takes about 70,000 hand-picked flowers to harvest one pound of saffron.
3
Supports Healthy Brain Chemistry at the Source
Many antidepressants work by blocking the reuptake of serotonin, which can still leave your brain low on the actual supply. SAMe works differently by supporting your body's ability to make serotonin (and other important brain chemicals) naturally, helping restore balance from the ground up.
🧠 Bonus: Studies suggest SAMe may work faster than many prescription options.
4
Physician Formulated for Real Results
Every Nedley Health supplement is created by Dr. Neil Nedley, MD — an internal medicine physician with decades of experience in lifestyle and nutritional medicine. Our formulas are based on clinical evidence, not trends, and are designed to support your body’s natural processes.
5
Clean Ingredients You Can Trust
No fillers, dyes, or artificial additives — just pure, potent nutrients sourced for maximum bioavailability. Every batch is tested to ensure safety, purity, and potency so you can supplement with confidence.
✅ Non-GMO, gluten-free, and sustainably sourced.
6
Trusted by Thousands for Brain and Mood Health
Nedley Health has helped thousands improve mood, clarity, and resilience with physician-developed education and supplementation. Mood continues that mission — giving you a natural, research-backed way to feel better without compromising your long-term health.
A product that really works!
Every product l have purchased from this Doctor has worked tremendously. Taking Mood for only a short time l could feel the difference. My family has taken notice in my outlook/disposition. This was such a good investment. Thank you Dr. Nedley.
Catherine R
Verified Buyer
GMO Free
Evidence-Based
Vegan Friendly
No Added Sugar
Made in USA
No Artificial Colors
GMO Free
Evidence-Based
Vegan Friendly
No Added Sugar
Made in USA
No Artificial Colors
Free shipping on all US orders of $99 or more
Rated 4.53/5 100+ Happy Customers
Mood by Nedley Health
Natural Support For Your Mood
Supports mental clarity and sharpness
Enhances mood, stress management, and alleviates depression
Promotes emotional stability during hormonal changes
30 Daily Doses Delivered Monthly
FREE & Fast Delivery
Risk-Free 30 Days
Physician Formulated
Ships in 1 Business Day
Formula & Ingredients
Saffron Stigma Extract – 20 mg
Saffron is prized for its ability to support healthy serotonin activity in the brain, a key factor in mood regulation. Clinical studies suggest saffron may help improve mood and emotional balance. Known as the world’s most expensive spice, saffron is hand-harvested from delicate crocus flowers—requiring around 70,000 blooms to produce just one pound of stigmas.
S-Adenosyl Methionine (SAMe) – 200 mg
SAMe is a naturally occurring compound in the body that helps produce neurotransmitters like serotonin, dopamine, and norepinephrine—essential for mood, motivation, and emotional stability. Research shows SAMe can support a healthy mood and emotional well-being, while also benefiting joint health and liver function. Supplementation helps restore optimal levels, promoting clarity and resilience.
How Does It Work?
Mood combines two clinically studied ingredients—Saffron and SAMe—that work together to support healthy brain chemistry. Saffron helps maintain balanced serotonin levels, while SAMe provides the building blocks your body needs to produce key neurotransmitters like dopamine and norepinephrine. The result is a gentle, natural approach to improving mood, emotional balance, and mental clarity—without the side effects often associated with synthetic options.
How Do I Take It?
Dr. Nedley recommends taking 2 capsules daily, preferably in the morning with food. Taking Mood at the same time each day can help your body maintain steady levels of its active ingredients.
Warnings: Not intended for persons under the age of 12. Consult a health care professional prior to consumption if you are pregnant, nursing, have a pre-existing medical condition, take medications or take other supplements with zinc, biotin, P5P or Vitamin B-6. Improper use of this product will not improve results and is potentially hazardous to a person’s health. Use only as directed.
How Long Do I Use It Before Seeing Results?
Some people notice a difference within the first week, but research suggests the most consistent benefits appear after 4 to 6 weeks of daily use. Because Mood works by supporting your body’s natural chemistry, the effects can build gradually over time—helping you feel more steady, resilient, and like yourself again.
100%
Money-back Guarantee
Feel Your Best.
Think Your Best.
Your brain health is our top priority. If you’re not satisfied with your supplement, we’ll offer personalized support — and if it still doesn’t meet your needs, you’re backed by our 60-day 100% money-back guarantee. No hassle, no pressure.
Real People. Real Results.
It helped elevate my mood!!!
It helped elevate my sad tired feeling to happy and more energy!
Barbara C
Verified Buyer
Already see results in...
Already see results in short time in my brother. Amazing!
Pat D
Verified Buyer
Excellent help for reducing anxiety.
I had recently begun suffering from anxiety, some depression, and trouble sleeping. It has helped reduce my anxiety and I've been sleeping MUCH better! So, I love this product! Thank you.
Linda R
Verified Buyer
My son is able to live a normal life.
This set of supplements has helped my son feel much better. He was able to eliminate his anxiety and depression as long as he takes it regularly.
Wendy C.
Verified Buyer
Works well for me
I've used 2 bottles of it now, and I like it very much. I notice a difference if I don't use it.
Constance C
Verified Buyer
Very positive experience.
As a health care professional myself I'm skeptical of vitamins and medicine. I trust Dr Nedley and believe the pathophysiology and science behind his vitamins. This makes sense. So I tried it, and they work. Thank You!
Karl A
Verified Buyer
Amazing supplement.
Better then antidepressants.
Marvin H
Verified Buyer
No more feelings of morning grogginess!
I’m taking this once every morning and finding that I wake up the next not feeling groggy which happened in the past. So very happy with this product!
Jennifer T
Verified Buyer
Thank you so much!
I suffer from deep depression. I was to the point that I didn't look forward to anything. I had absolutely no energy for anything. After about two weeks I started to feel more like my old self. Looking forward to doing things with my family and my church.
Catherine G.
Verified Buyer
VERY impressed! I feel WONDERFUL!!!
Natural and non-addictive, that's the most important to me, also that it helps me feel sooo good. I hate feeling down & totally out of it. Thank-you for a wonderful product! God Bless you!!!
Paula
Verified Buyer
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Frequently Asked Questions
How is this different from other brain supplements on the market?
Unlike generic formulas, Nedley Health supplements are physician-formulated using clinically studied ingredients at therapeutic doses — designed to support cognitive performance without relying on stimulants or artificial additives.
Who is this supplement for?
Mood is for adults who want a natural, research-backed way to support emotional well-being. It can be helpful for those experiencing occasional low mood, motivation dips, or stress, as well as those seeking ongoing mood maintenance.
Are these supplements safe to take daily?
Yes. Our formulas are non-habit forming and made with naturally derived, third-party-tested ingredients to ensure purity, potency, and safety for daily use.
What makes Dr. Nedley’s approach unique?
Dr. Neil Nedley is a board-certified physician and author with over 25 years of clinical experience in lifestyle-based mental health. These supplements are backed by his proven protocols, used in thousands of successful recoveries.
Do I need to be diagnosed with a condition to benefit?
Not at all. You don’t need a formal diagnosis to benefit from Mood. Its ingredients support healthy brain chemistry, which can help anyone looking to promote a balanced mood, emotional resilience, and mental clarity—whether you’re going through a rough patch or simply want to feel your best.
Can I take this alongside other vitamins or medications?
Most people can safely combine Mood with their existing routines. However, we always recommend checking with your healthcare provider—especially if you’re on prescription medications, antidepressants, or managing a medical condition.
