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Circulation
- Supports healthy cholesterol and blood flow*
- Physician-formulated formula for whole-body circulation
- 3 clinically studied, naturally sourced ingredients
Cancel anytime. Shipping and tax apply at checkout.
How your subscription works
Circulation is added as its own subscription, with its own charge date. Your first order ships right away. Your chosen supply renews automatically: $55.24 monthly, $155.98 every 3 months, or $292.46 every 6 months. Cancel anytime before a future charge.
3 researched ingredients. A closer look.
Select an ingredient to see what it supports and what the research says.
One of the most studied botanicals for healthy cholesterol and circulation, and the core of this formula. It works on both sides of the equation at once: the lipid markers, and the blood vessels those lipids move through. Circulation delivers the full 1,000 mg per daily serving, the amount used in the human trials.
Supports
- LDL cholesterol
- HDL cholesterol
- Blood sugar
- Vessel function
In published trials
Across two 12-week randomized, double-blind, placebo-controlled trials, a standardized amla extract at 1,000 mg daily lowered LDL cholesterol by 20 to 22 percent and total cholesterol by 11 to 24 percent from baseline, with significant differences versus placebo. Blood-vessel function improved alongside it, including a 51 percent rise in nitric oxide.
Upadya H, et al. BMC Complement Altern Med. 2019;19:27 · Usharani P, et al. BMC Complement Altern Med. 2019;19:97 · corroborated by Setayesh L, et al. Diabetes Metab Syndr. 2023;17(3):102729
Antioxidant capacity, measured in the lab See the laboratory antioxidant testing
ORAC is a laboratory test of how well a substance neutralizes free radicals in a test tube. It is a measure of the ingredient, not of an effect in the body. On that test, this amla extract scores well above the fruits usually held up as antioxidant benchmarks.
H-ORAC values assayed in vitro by Brunswick Laboratories. Laboratory antioxidant scores have not been shown to predict effects in the human body.
Why free radicals matter here: when blood sugar runs high, sugars bind to proteins and form advanced glycation end products, or AGEs, the compounds that stiffen tissue and drive oxidative stress. In laboratory and animal research, amla extracts strongly inhibited AGE formation and scavenged free radicals. That work has not yet been repeated in humans, but it is the reason this ingredient sits at the center of a formula built for cholesterol and blood sugar together. Rao TP, Sakaguchi N, Juneja LR, et al. J Med Food. 2005;8(3):362-368 (animal model) · Sharma P, et al. Appl Sci. 2021;11(19):8819 (in vitro).
A plant alkaloid used for centuries in traditional practice. It earns its place here because the evidence covers both halves of what this formula is built for, rather than one or the other. It is one of the few botanicals with pooled placebo-controlled data spanning LDL cholesterol and blood sugar together.
Supports
- LDL cholesterol
- Blood sugar
In published trials
In a 2023 systematic review and meta-analysis of 18 randomized placebo-controlled trials, berberine at 900 to 1,500 mg daily lowered LDL cholesterol by an average of 0.46 mmol/L, roughly 18 mg/dL, in adults with dyslipidemia.
Blais JE, Huang X, Zhao JV. Drugs. 2023;83(5):403-427
Your body requires chromium for normal macronutrient metabolism, and it is the ingredient covering the HDL side of the picture. Specified as Albion® chromium nicotinate glycinate, a chelated form built for absorption rather than the cheaper picolinate most formulas reach for.
Supports
- A1c
- HDL cholesterol
In published trials
Pooled analyses of randomized trials in adults with type 2 diabetes reported A1c reductions in the range of roughly 0.5 to 0.7 points, alongside an increase in HDL cholesterol of about 5 mg/dL.
Asbaghi O, et al. Pharmacol Res. 2020;161:105098 · Huang H, et al. Mol Nutr Food Res. 2018;62(1)
Research cited is on individual ingredients; study doses and forms may differ from this formula. Results are not guaranteed. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Nedley Health customer reviews
Reviews from customers across Nedley Health products—not exclusively Circulation.
Good to know.
Who can claim a free bottle?
This fall thank-you offer is for active Nedley Health subscribers who are not already subscribed to Circulation. Add Circulation as a subscription September 24–28, 2026. One-time purchases do not qualify.
How does the free bottle work?
Every option includes one free bottle at that plan’s subscription rate on the first charge. First-order totals are rounded to the nearest cent. Pay $0 for your first 1-month supply, $103.99 for 3 months, or $243.72 for 6 months. Shipping and tax applies at checkout. Your free-bottle credit applies to the first charge only.
What will I pay on renewal?
Your chosen supply renews at $55.24 monthly (15% savings), $155.98 every 3 months (20% savings), or $292.46 every 6 months (25% savings). Cancel anytime. Shipping and tax may apply.
Will it wait for my next subscription box?
No. Circulation has its own subscription and charge date, so your first order ships separately without waiting for your existing subscription schedule.
Can I cancel Circulation?
Yes. Cancel anytime before a future charge. Your other subscriptions stay as they are.
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